Anesthesia Experience Of A Patient With Myotonic Dystrophy

Use of Sugammadex in a Patient With Myotonic Dystrophy

One of the challenges during the perioperative care of patients with myotonic dystrophy is the reversal of neuromuscular blocking agents. Agents that inhibit acetylcholinesterase, such as neostigmine, may precipitate myotonia, and are therefore relatively contraindicated. Sugammadex is a novel pharmacologic agent, which encapsulates rocuronium or vecuronium, thereby reversing their effect. We r...

Opioid-free general anesthesia in patient with Steinert syndrome (myotonic dystrophy)

INTRODUCTION We report on the anesthetic management using opioid-free method of a patient with Steinert syndrome (myotonic dystrophy, MD), autosomal dominant dystrophy which is characterized by consistent contracture of muscle following stimulation. A myotonic crisis can be induced by numerous factors including hypothermia, shivering, and mechanical or electrical stimulation. In patients with M...

[Marked hyperinsulinemia in a patient with myotonic dystrophy].

Laparoscopic Cholecystectomy for Cholelithiasis in a Patient With Myotonic Dystrophy

Myotonic dystrophy (DM) is a rare autosomal dominant inherited neuromuscular disease involving several systems. The anesthetic method of choice remains uncertain. The risk of perioperative complications, particularly pulmonary and cardiac complications, in these patients is of major concern. We report on a 16-year-old female patient with DM type 1 undergoing laparoscopic cholecystectomy for sym...

Myotonic Dystrophy Type 1 with Syringomyelia in a Young Patient

Myotonic dystrophy type 1 (DM1) is the most common disease causing muscle weakness and atrophy in adults. The prevalence of DM1 in China is not clear. DM1 is an autosomal dominant genetic disorder associated with the cytosine‑thymine‑guanine (CTG) repeat expansion in 3'untranslated region in dystrophia myotonica‑protein kinase (DMPK) gene on chromosome 19q13.3. In DM1, CTG pathological repeat n...